Which of the following hematological condition is depicted below?
Correct Answer: Multiple myeloma
Description: Ref. Robbins Pathology. 9th edition. Page. 620
The picture shows many atpical plasma cells – Diagnostic of Myeloma
Malignant proliferation of plasma cells characterised by monoclonal gammaglobulinaemia (paraproteinaemia)
Cell of origin – Post germinal centre B cells
Stages
MGUS
Smoldering myeloma
Myeloma
MGUS – most common plasma cell dyscrasia
Myeloma – CRAB Features
Hypercalcemia
Renal Insufficiency
Anemia
Bone lytic lesions
Category:
Unknown
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