All of the following enzymes may contribute in generating free oxygen radicals within neutrophils for killing intracellular bacteria, except-
Correct Answer: Glutathione peroxidase
Description: NADPH oxidase called the phagocyte oxidase, which oxidizes NADPH (reduced nicotinamide adenine dinucleotide phosphate) and, in the process, conves oxygen to superoxide ion (O2 * ) Superoxide is then conveed by superoxide dismutase into hydrogen peroxide (O2 * + 2H+ - H2O2) glutathione peroxidase major function is to protect cells from oxidative damage by regeneration of glutathione. Fenton reaction: H2O2 + Fe2+ -Fe2++ OH- + OH. ref robbins basic pathology 9th ed page 38
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now