Which one of the following is not an intravesical chemotherapeutic agent
Correct Answer: BCG
Description: American urologists use BCG by a 2 : 1 margin compared with intravesical adjuvant or maintenance chemotherapy (e.g., doxorubicin hydrochloride , gemcitabine, thiotepa), whereas European urologists or chemotherapy. BCG is approved for this indication by the U.S. Food and Drug Administration (FDA) . Mechanism of action of BCG . Intravesical immunotherapy results in a massive local immune response characterized by induced expression of cytokines in the urine and bladder wall and by an influx of granulocytes and mononuclear and dendritic cells . The initial step appears to be direct binding to fibronectin within the bladder wall, subsequently leading to direct stimulation of cell-based immunologic response and an antiangiogenic state. ref : Campbell - Walsh urology 11th ed , chapter 93 , pg no 2212
Category:
Surgery
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now