Thiamine deficiency in a chronic alcoholic can reduce energy production as a result of which of the following reasons?
Correct Answer: It is a co-enzyme for pyruvate dehydrogenase and a-ketoglutarate dehydrogenase in TCA pathway
Description: Thiamine is a co-enzyme for pyruvate dehydrogenase and a-ketoglutarate dehydrogenase in the TCA pathway. Both the steps of the TCA cycle have thiamine requiring enzymes are required for the aerobic generation of ATP through krebs cycle. So thiamine deficiency can result in decreased energy production. Ref: Textbook of biochemistry by DM Vasudevan, 3rd Edition, Page 268
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now