Which of the following is not associated with Adult Polycystic Kidney Disease

A. Autosomal dominant inheritance

B. Mutations involving gene affecting cell-cell-matrix interaction

C. Intracranial berry aneurysm may be present

D. Tricuspid valve prolapse

Correct Answer: Tricuspid valve prolapse

Description: ADPKD Inheritance: Autosomal dominant Cytogenetic defect: Chromosome 16 (85%): ADPKD-1 Chromosome 4 (15%): ADPKD-2 Mutations: PKD 1 gene (85%) & PKD 2 gene (15%) Other manifestations: Intracranial aneurysms, cysts of other organs. Ref: HARSH MOHAN TEXTBOOK OF PATHOLOGY 6th ed. pg no: 659

Category: Pathology

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