Which of the following is a radioprotector
Correct Answer: Amifostine
Description: Amifostine:- It is an organic thiophosphate which on activation by alkaline phosphatase acts as a cytoprotective against cancer chemotherapy and radiotherapy. Uses:- It is paicularly used for prophylaxis of cisplatin induced neuro/nephrotoxicity, and radiotherapy related xerostomia. Adverse effects:- Sho term side effects of amifostine are nausea, vomiting, hypotension and infusion related reaction. Delayed adverse effect is hypocalcaemia. Ref:- kd tripathi; pg num:-876
Category:
Pharmacology
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