The gene that regulates normal morphogenesis during development is –
Correct Answer: Homeobox gene.
Description: Ans. is 'b' i.e., Homeobox geneHomeobox geneo is associated with normal morphogenesis.o Their expression results in the production of localized cellular condensation of primitive mesenchyme in the sites of future bones.o They play an impoant role in patterning of limbs, veebrae and craniofacial structures.o Mutations in Homeobox gene produces an extra digit between 3rd and fouh fingers as well as some degree of syndactyly.About other options :?o FMR gene : It is familial mental retardation gene mutation in this gene causes Fragile-X- syndromeo PTEN : It is phosphatase and tensin homologue. It is frequently deleted in many human cancers such as Glioblastomas, Prostate cancers, Endometrial cancers and Breast cancer.o P-16 : It is a tumour suppressor gene.
Category:
Pathology
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