A boy comes with complains of vomiting, bloated abdomen and abdominal pain. He has a history of attending ice–cream eating competition last night. Ile also has a past history of similar episodes following ingestion of milk and milk products. The likely cause –
Correct Answer: Lactase deficiency
Description: History of ice cream ingestion and subsequent symptoms of vomiting, bloated abdomen, are characteristic findings of lactase deficiency.
Lactase deficiency -
Lactase is a disaccharidase present on intestinal epithelium (brush border)*. It is used to digest lactose (disaccharide).
Symptoms arise after ingestion of food containing lactose (e.g. milk).
Symptom - Diarrhoea, vomiting, bloated abdomen.
Diagnosis
Presence of more than 1/2 percent of reducing substrate in the fresh stool.
Acidic stools
Abnormal oral sugar tolerance test* (blood glucose rise of less than 20mg/d1 above fasting level with a disaccharide load of 2g/kg)
Breath H2 excretion of more than 11 ppm*.
Enzyme assay on mucosal biopsies showing low levels of disaccharidases.
Treatment -
low lactose diet.
Category:
Pediatrics
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