All are used in gluconeogenesis except
Correct Answer: Oleate
Description: GLUCONEOGENESIS 1. Definition - It is the process by which glucose molecules are produced from non-carbohydrate precursors. These include lactate, glucogenic amino acids (Alanine, glutamic acid, aspaic acid, etc), glycerol pa of fat and propionyl CoA derived from odd chain fatty acids. 2. Site - Gluconeogenesis occurs mainly in the liver, and to a lesser extent in the renal coex. The pathway is paly mitochondrial and paly cytoplasmic. 3. Key Gluconeogenic Enzymes Pyruvate carboxylase Phosphoenol pyruvate carboxy kinase Fructose-1-6-bisphosphatase Glucose-6-phosphatase . Propionyl CoA as a substrate in gluconeogenesis - Propionyl CoA is formed from odd chain fatty acids and carbon skeleton of some amino acids. It is conveed to succinyl CoA. It is a minor source for glucose. Ref: DM VASUDEVAN TEXTBOOK OF BIOCHEMISTRY, EIGHTH EDITION, PG.NO., 135,136,138.
Category:
Biochemistry
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