Which of the following induction agent may cause adrenal coex suppression?
Correct Answer: Etomidate
Description: Etomidate is an induction anaesthetic which cause suppression of production of steroids from adrenals. It is therefore not suitable for continuous intravenous use. It has brief duration of action (5-10min) and produce little cardiovascular and respiratory depression. It produce prominent motor restlessness and rigidity. Use of etomidate should be restricted to clinical situations in which its hemodynamic stability offers a distinctive advantage over the other available induction drugs (e.g. elderly outpatients with clinically significant coronary aery or cerebrovascular disease). Ref: Essentials of Medical Pharmacology By K D Tripathi, 5th Edition, Pages 342-4
Category:
Anaesthesia
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