100 % Filtration Coefficient is seen in?
Correct Answer: Inulin
Description: ANSWER: (D) InulinREF: Guyton 11th edition page 184, 344FILTRATION COEFFICIENT:Filtration coefficient is a measure of a membrane's permeability to water, taking into account both hydraulic and osmotic pressures.(Note: Filtration coefficient 100= Filterability 1)Filterability of Solutes Is Inversely Related to Their Size.The glomerular capillary membrane is thicker than most other capillaries, but it is also much more porous and therefore filters fluid at a high rate.Despite the high filtration rate, the glomerular filtration barrier is selective in determining which molecules will filter, based on their size and electrical charge. A filterability of 1.0 as in case of inulin means that the substance is filtered as freely as waterInulin Clearance Can Be Used to Estimate GFR:If a substance is freely filtered (filtered as freely as water) and is not reabsorbed or secreted by the renal tubules, then the rate at which that substance is excreted in the urine is equal to the filtration rate of the substance by the kidneys.
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