All of the following use c-AMP as a secondmessenger except
Correct Answer: Vasopressin
Description: Vasopressin Coicotropin, Dopamine & Glucagon use cAMP as second messenger Vasopressin uses both phosphatidylinositol & cAMP as second messengers Vasopressin has three kinds of receptors ? - act through phosphatidylinositol hydrolysis - V1B to increase the intracellular Ca2+ concentration - V2 act through G5 to increase cAMP levels. So Vasopressin is our best option as only V2 receptors use cAMP as second messenger Dopamine acts through 5 receptors: D1, D2, D3, D4 & D5. D1 & D5 T cyclic AMP levels & D2, D5, D4 cyclic AMP levels. I. Hormones that bind to intracellular receptors Androgens Calcitriol (1,25[01-1_12-D3) Estrogens Glucocoicoids Mineralocoicoids Progestins Retinoic acid Thyroid hormones (T3 and T4) II. Hormones that bind to cell surface receptors A. The second messenger is cAMP a2-Adrenergic catecholamines b-Adrenergic catecholamines Adrenocoicotropic hormone (coicotropin) Antidiuretic hormone (Vasopressin V2) Calcitonin Chorionic gonadotropin. human Coicotropin-releasing hormone Dopamine Follicle-stimulating hormone Glucagon Lutenizing hormone Melanocyte-stimulating hormone Parathyroid hormone Somatostatin Thyroid-stimulating hormone B. The second messenger is cGMP: Atrial natriuretic factor Nitric oxide C. The second messenger is calcium or phosphatidylinositols (or both): Acetylcholine (muscarinic) oci-Adrenergic catecholamines Angiotensin II Antidiuretic hormone (vasopressin & Cholecystokinin Gastrin Gonadotropin-releasing hormone Oxytocin Thyrotropin-releasing hormone D. The second messenger is a kinase or phosphatase cascade : Chorionic somatomammotropin Erythropoietin Growth hormone Insulin Insulin-like growth factors I and II Prolactin
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