Which of the following disorders is least likely to be associated with a prolonged bleeding time?
Correct Answer: Coagulation factor deficiencies
Description: ConditionProthrombin timeActivated paial thromboplastin timeBleeding timePlatelet countThrombocytopeniaUnaffectedUnaffectedProlongedDecreasedVon Willebrand diseaseUnaffectedProlonged or unaffectedProlongedUnaffectedUremiaUnaffectedUnaffectedProlongedUnaffectedHemophiliaUnaffectedProlongedUnaffectedUnaffectedFactor XII deficiencyUnaffectedProlongedUnaffectedUnaffectedC1 deficiencyUnaffectedShoenedUnaffectedUnaffectedAspirinUnaffectedUnaffectedProlongedUnaffectedCongenital afibrinogenemiaProlongedProlongedProlongedUnaffectedVitamin K deficiency or warfarinProlongedNormal or mildly prolongedUnaffectedUnaffectedLiver failure early Prolonged Unaffected Unaffected Unaffected Liver failure, end-stageProlongedProlongedProlongedDecreasedFactor V deficiencyProlongedProlongedUnaffectedUnaffectedFactor X deficiency as seen in amyloid purpuraProlongedProlongedUnaffectedUnaffectedBernard-Soulier syndromeUnaffectedUnaffectedProlongedDecreased or unaffectedDisseminated intravascular coagulationProlonged Prolonged Prolonged Decreased Glanzmann's thrombasthenia UnaffectedUnaffectedProlonged Unaffected(Refer: Harrison's Principles of Internal Medicine, 18th edition, pg no: 461-464)
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