BRCA1 gene is associated with
Correct Answer: Mucinous carcinoma
Description: Ans is 'b' i.e. Mucinous carcinoma "Medullary carcinomas and mucinous carcinomas histological types are more commonly found in BRCA1 carrier". -- Robbings 1134Familial breast cancero About 25% offamilial cancers (or around 3% of all breast cancer) can be attributed to two highly penetrant autosomal dominant genes BRCA-1 on chromosome 17 (52%) and BRCA-2 on chromosome 13 (32%).o Germ line mutation in p53 also increases the risk of breast cancer along with cancers of colon, leukemia, sarcoma and brain tumors (Li fraumeni syndrome)o Somatic mutation in p53 - Sporadic breast cancero Germ line mutation in BRCA-1, BRCA-2, and p53 - Familial breast cancer.
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