Long term use of aspirin in rheumatoid ahritis is limited by its propensity to cause:
Correct Answer: Gastric mucosal damage
Description: All non-selective COX inhibitors including aspirin on long-term used can cause gastric toxicity ranging from gastritis to peptic ulcer. Selective COX-2 inhibitors have lesser propensity to cause this adverse effect. Salicylism and metabolic acidosis are seen in overdose, not with long term use.
Category:
Pharmacology
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