Prolactin secretion increased by all EXCEPT
Correct Answer: Dopamine
Description: Dopamine REF: Harrison's 17 edition chapter 333 Table 333-8"Dopamine is the primary neuroendocrine inhibitor of the secretion of prolactin from the anterior pituitary gland and hence causes hypoprolactinemia not hyperprolacinnemia"ETIOLOGY OF HYPERPROLACTINEMIAPhysiologicHypothalamic-PituitarySystemicDrug-inducedhypersecretionpituitary stalkdamagehypersecretiondisordershypersecretionPregnancyTumorsProlactinomaChronic renalPhenothiazines,LactationChest wallCraniopharyngiomaSuprasellar pituitaryAcromegalyfailureHypothyroidismchlorpromazine,perphenazinestimulationmass extension CirrhosisHaloperidolSleepMeningioma PseudocyesisMetoclopramideStressDysgerminoma Epileptic seizuresMethyldopa Metastases Reserpine Empty sella Opiates Lymphocytichypophysitis Cimetidine,ranitidine Adenoma with stalkcompression Amitriptyline,Amoxapine Granulomas Fluoxetine Rathke's cyst Verapamil IrradiationTraumaPituitary stalksection Estrogens,Antiandrogen,TRH Suprasellar surgery
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