Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.  The parasite is transmitted through the bite of a female Anopheles mosquito and causes the disease's most dangerous form, falciparum malaria.  Unlike those of other Plasmodium species, the gametocytes of P. falciparum are elongated and crescent-shaped, by which they are sometimes identified.  A mature gametocyte is 8–12 μm long and 3–6 μm wide.  Haemozoin is a disposal product formed from the digestion of blood by some blood-feeding parasites, the hematophagous organisms such as malaria parasites (Plasmodium spp.).  In Plasmodium the food vacuole fills with hemozoin crystals, which are about 100-200 nanometres long and each contain about 80,000 heme molecules. Detoxification through bio-crystallization is distinct from the detoxification process in mammals, where an enzyme called heme oxygenase instead breaks excess heme into biliverdin, iron, and carbon monoxide.Ref :https://en.wikipedia.org/wiki/Plasmodium_falciparum#:~:text=Plasmodium%20falciparum%20is%20a%20unicellular,most%20dangerous%20form%2C%20falciparum%20malaria https://en.wikipedia.org/wiki/Hemozoin