Cause of liver cirrhosis in childhood include –
Correct Answer: Alpha–1 antitrypsin deficiency
Description: Cirrhosis in children
Cirrhosis is a histologically defined condition of the liver characterized by diffuse hepatocyte injury and regeneration.
Causes of cirrhosis in children are -
1) Post necrotic
Viral hepatitis -p HBV, HCV ❑ Idiopathic neonatal hepatitis o-antitrypsin deficiency
Autoimmune or drug induced hepatitis ❑ Wilson disease ❑ Hethochromatosis
Tyrosinemia ❑ Galactosemia
2) Biliary
Biliary atresia ❑ Choledochal cyst ❑ Tumor of bile duct
Caroli disease ❑ Cystic fibrosis ❑ Primary sclerosing cholangitis
PFIC ❑ Paucity of intrahepatic bile ducts
3. Hypersensitivity to drug -3 Phenytoin
4. Parasites -3 Opisthorchis sinensis, Ascaris, Fasciola.
Category:
Pediatrics
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