Danazol is: September 2006
Correct Answer: Antiandrogens
Description: Ans. C: Antiandrogens Danazol is a derivative of the synthetic steroid ethisterone, a modified testosterone. (It is also known as 17alpha-ethinyl testosterone). Though labeled as an impeded/attenuated androgen, because it binds to the androgen receptor and induces some androgen specific mRNA production, the most prominent action is suppression of Gn secretion from pituitary in both men and women. Although effective for endometriosis, menorrhagia and fibrocystic breast disease, its use is limited by its masculinizing side-effects.
Category:
Pharmacology
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