Barbiturates act on which step of mitochondrial respiratory chain:
Correct Answer: Complex I to Co-enzyme Q
Description: option a : Barbiturates such as amobarbital inhibit electron transpo Complex I by blocking the transfer from complex I to Coenzyme Complexes Inhibitors of ETC Complex I (NADH-CoQ reductase/NADH dehydrogenase) Rotenone, Phenobarbitone, Amobarbital, Piericidin A Complex II (Succinate CoQ reductase) Malonate (3C) Carboxin (Fungicide) TTFA (Trienoyl Tri Fluoro Acetone) Complex III (Cyt c reductase) Phenoformin Antimycin A BAL (British Anti Lewisite) or Dimercaprol) Complex IV (Cyt c oxidase) CO Cyanide (CN), H2S, Sodium Azide Uncouplers of ETC: Dinitrophenol, Thermogenin ADP to ATP conversion is inhibited by: Oligomycin ADP to ATP transfer is inhibited by: Atractyloside
Category:
Biochemistry
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