Reducing equivalants produced in glycolysis are transported from cytosol to mitochondria by –
Correct Answer: Malate shuttle
Description: Ans. is 'c' i.e., Malate shuttle o Most of the NADH and FADH2, entering the mitochondrial electron transport chain arise from citric acid cycle and b-oxidation of fatty acids, located in the mitochondria itself.o However, NADH is also produced in the cytosol during glycolysis.o To get oxidized, NADH has to be transported into the mitochondria as respiratory chain (ETC) is located inside the mitochondria.o Since, the inner mitochondrial membrane is not permeable to cytoplasmic NADH, there are special shuttle systems which carry reducing equivalents from cytosolic NADH (rather than NADH itself) into the mitochondria by an indirect route.o Two such shuttle systems that can lead to transport of reducing equivalent from the cytoplasm into mitochondria are: -Malate shuttle (malate-aspartate shuttle system).Glycerophosphate shuttle.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now