First line therapy in smoking dependence:
Correct Answer: Nicotine replacement gum
Description: (Ref: Katzung, 14th ed. pg. 584)Treatment of smoking dependence:* First line: Nicotine replacement therapy (gum, patch, inhaler).* Bupropion and Varenicicline (Nicotine receptor agonist): Also, first line. Considered more effective.* 2nd line: Clonidine and Nortryptiline* Rimonabant: Cannabinoid receptor inverse agonist. Withdrawn due to increased depression and suicide risk.
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