Clearance of the following substance is the hallmark experimental method of measuring the GFR:
Correct Answer: Inulin
Description: Inulin is a polysaccharide starch of about 5-kD molecular weight that is not usually found in the body. It is freely filtered by the glomerulus, but it is not reabsorbed or secreted by the nephron. All the inulin that is filtered flows through the nephron and appears in the urine. Thus, the renal clearance of inulin is relatively large. Inulin in the blood is not taken up by other tissues, and the kidneys are the only excretion route. Thus, inulin clearance is indeed the hallmark experimental method of measuring the GFR. Ref: Eaton D.C., Pooler J.P. (2013). Chapter 3. Clearance. In D.C. Eaton, J.P. Pooler (Eds), Vander's Renal Physiology, 8e.
Category:
Physiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now