A laboratory analysis report of a specific fraction of a patient’s lymphocytes the following: HLA, Band C+,PHA+, CD3-, CD16+, CD11a/ CD18+, CD56+, and in vitro blastogenesis with IL12 What are the lymphocytes this set describes?
Correct Answer: Natural killer cells
Description: NK cells do not express a cell surface TCRlCD3 complex and are CD4-. About half of human NK cells are CD8+. Also, most NK cells express an Fe IgG receptor, known as CDI6, and CD56, a neural cell adhesion molecule variant. NK cells are generally CD16+, CD56+, and CD3-, which contrasts them with I cells which are CD3+, CDl6-, and CD56
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