A 30 year old lady presents with features of malabsorption and iron deficiency anaemia. Duodenal biopsy shows complete villous atrophy, Probable diagnosis can be asceained on detection of which antibody :
Correct Answer: Antiendomysial antibodies
Description: Differential diagnosis of this patient is Celiac disease Best screening test for diagnosis of celiac sprue -anti-Tissue transglutaminase antibody > Anti-endomyosial antibody Malabsorption and anemia is seen due to proximal gut > distal pa of small intestine Biopsy from Distal duodenum or proximal jejunum - loss or blunting of intestinal mucosa.
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