Ketone bodies are used by all except –
Correct Answer: Hepatocytes
Description: Ans. is 'd' i.e., Hepatocytes o Ketone bodies are synthesized by liver and are utilized by extrahepatic tissues like heart, muscles, renal cortex and brain (in starvation). o Liver cannot utilize ketone bodies because it lacks enzyme succinyl-CoA-acetoacetate CoA transferase, which is required for the activation of ketone bodies, o The first reaction in use of ketone bodies is activation of acetoacetate. o Liver lacks the enzyme CoA transferase; hence cannot utilize ketone bodies. RBCs can't use fatty acids because they don't have mitochondria
Category:
Biochemistry
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