Murmur increasing with Valsalva manouvre –
Correct Answer: HCM(hyperophic cardio myopathy)
Description: Increases 65% of the time with hyperophic cardiomyopathy; decreased 30% of the time; Increased intensity 65% sensitive and 96% specific for hyperophic cardiomyopathy as opposed to other lesions Most other murmurs decreased intensity during Valsalva. Physiologic explanation: murmur intensity increases with decreased LV volume because of increased proximity of septum and mitral valve; decreased venous return with Valsalva Ref Harrison 20th edition pg 1446
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