Which of the following is a feature of Marfan&;s syndrome?

Correct Answer: Subluxuation of lens
Description: Subluxuation of lens is associated with Marfan&;s syndrome. Features of Marfan&;s syndrome Mitral valve prolapse Myopia due to upward dislocation of lens (bilateral ectopic lentis) Aoic root dilatation, Aoic regurgitation Retinal detachment Fibrillin 1 gene defect: Reduced fibrillin 1 production causing joint laxity Fifteen (chromosome 15 is invloved) Flat feet Arachnodactyly, Astigmatism, Air in lungs (Pneumothorax) Near Sightedness Subluxuation of lens, Scoliosis, Speech disorders, Sleep apnea Ref: Nelson textbook of pediatrics 21st edition Pgno: 3741
Category: Pediatrics
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