Superantigens true is –
Correct Answer: Directly attached to lateral aspect of TCR b chain
Description: Superantigens are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. Superantigens bind first to the MHC Class II and then coordinate to the variable alpha or beta chain of T-cell Receptors . Reff: Ananthanarayan & Panikers textbook of microbiology 9th edition pg:90
Category:
Microbiology
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