A patient is suffering from SLE. On immunofluorescence showed granular deposits at the dermoepidermal junction. What is the constituent in these depostis?
Correct Answer: Immune complex deposits
Description: Immunofluoresence in dermatology Disease IgG IgM IgA C3 Flbrin IF pattern Antigen Pemphigus Vulgaris ++ ++ Intercellular- between epidermal cells Network pattern Desmoglein 3 Ig A pemphigus ++ Do Paraneoplastic pemphigus + + + + Do Desmoplakin Bullous pemphigoid ++ ++ Linear deposits along BMZ BP230 BP180 Epidemolysis bullosa aquisita ++ ++ do Collagen 7 Dermatitis Herpatiformis ++ + Granular papillary tip deposits along BMZ Epidermal transglutaminase SLE ++ ++ ++ Granular deposits along BMZ Lichen planus + + + + ++ Ovoid bodies with ragged fibrin band along BMZ Bollous SLE + ++ Linear BMZ deposits Collagen 7 Porphyria ++ + Perivascular and BMZ deposits Amyloid + ++ ++ ++ Globular deposits in tips of apillary dermis
Category:
Pathology
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