Neurological worsening with anemia what is the treatment to be given:
Correct Answer: Folic acid along with Hydroxycobalamin
Description: Vitamin deficiency Manifestation In folate megaloblastic anemia B12 Megaloblastic anemia & neurological manifestations occur. Clinical manifestations of B12 deficiency: Haematological: Megaloblastic anemia, Hypersegmentation of neutrophils. Neurological: Demyelination in peripheral nerves and spinal cord Megaloblastic anemia is due to secondary deficiency of folate (folate trap in B12 deficiency) Peripheral neuropathy is due to accumulation of L-methyl malonic acid.
Category:
Biochemistry
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