Why is Glucose-6-phosphate is not acted upon by Glucose-6-phosphatase enzyme in cytoplasm, even if glycogen synthesis and breakdown takes place in the same cell, having an enzymes present in cytoplasm.
Correct Answer: Glucose-6-phosphatase is present in endoplasmic reticulum while glycogen metabolism occurs in the cytoplasm
Description: Glycogen synthesis as well as breakdown both occurs in cytoplasm But the last step of breakdown of glycogen in liver i.e. glucose -6-phosphate to glucose formation occurs in endoplasmic reticulum and not in cytoplasm, as glucose-6-phosphatase is present in the membrane of endoplasmic reticulum.
Category:
Biochemistry
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