Which of the following tests is not used for detection of specific aneuploidy:
Correct Answer: Microarray
Description: D i.e. Microarray - FISH (Fluorescent in situ hybridisation) and PCR (polymerase chain reaction) like -PCR and QF PCR tests can detect specific anemploidyQ. - Whereas, microarray based CGH (comparative genomic hybridization) test can be used as high resolution whole genome scan for the detection or screening of unknown (non specific) abnormalities, mutation or genomic imbalance including deletions, duplication and aneuploidies. Microarray based CGH cannot detect balanced translocations or inversions. So FISH and PCR can detect specific (known) chromosomal abnormalities whereas microarray based CGH is better suited for screening unknown (non specific) chromosomal abnormalities.
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