Which of the following statements about Cushing’s disease is true?
Correct Answer: Pituitary microadenoma usually is present
Description: Cushing’s syndrome is due to increased adrenal cortisol production, regardless of etiology.
Cushing’s disease usually is caused by a pituitary microadenoma producing high adrenocorticotropin (ACTH) levels.
In most patients, cortisol levels would be suppressed as a result of the high-dose dexamethasone suppression test.
Transsphenoidal microsurgical removal of the microadenoma is the treatment of choice in most centers.
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