All are impoant laboratory features of hereditary spherocytosis, EXCEPT:

Correct Answer: Reduced MCHC
Description: Laboratory diagnosis of hereditary spherocytosis The anemia is usually normocytic. Increase in mean corpuscular hemoglobin concentration (MCHC)- (The only condition in which an increased MCHC is seen.) The diagnosis is on the basis of red cell morphology and osmotic fragility, a modified version called the pink test. Ref: Harrison, E-18, P-875.
Category: Medicine
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