Diagnostic criteria for Allergic Bronchopulmonary Aspergillosis include all, except
Correct Answer: Peripheral eosinophilia (>0.1 x 109/mm3)
Description: Answer is A (Peripheral eosinophilia (>0.1 x 109/mm3): Peripheral blood eosinophilia with eo.sinophil count >1000/mm3 is included in the primary diagnostic criteria (and not an eosinophil count > 0.1 x 109/mm3) Criteria for the Diagnosis of ABPA Primary Primary Episodic bronchial obstruction (asthma) Peripheral blood eosinophilia (>1000/mm3) Elevated serum IgE concentrations (>100Ong/m1) Immediately type skin reactivity to Aspergillus antigens Precipitating serum antibodies (precipitants) against Aspergillus antigens Elevated serum IgE and/or IgG antibodies specific to A. fumigatus * History of pulmonary infiltrates (transient/fleeting or fixed) on chest radiographs or CT scans Central proximal bronchiectasis on chest CT Secondary A. fumigatus in sputum (by repeated culture or microscopic examination) History of expectoration of brown plugs or flecks Ahus reactivity (late skin reactivity) to Aspergillus antigen *Elevated IgE (and IgG) class antibodies specific for A. fumigatus has been mentioned as a secondary diagnostic criteria in Harrison's textbook while Fishman's textbook includes this as a main/major diagnostic criteria.
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