All of the following are true about mitochondria except
Correct Answer: Mitochondrial diseases are paternal in inheritance
Description: "Over a billion years ago, aerobic bacteria were engulfed by eukaryotic cells and evolved into mitochondria, providing the eukaryotic cells with the ability to form the energy-rich compound ATP by oxidative phosphorylation. Mitochondria perform other functions, including a role in the regulation of apoptosis (programmed cell death), but oxidative phosphorylation is the most crucial." Consistent with their origin from aerobic bacteria, the mitochondria have their own genome. As a zygote, mitochondria are derived from the ovum, their inheritance is maternal. This maternal inheritance has been used as a tool to track evolutionary descent. Mitochondria have an ineffective DNA repair system, and the mutation rate for mitochondrial DNA is over 10 times the rate of nuclear DNA.Reference: Ganong's Review of Medical Physiology; 25th edition; Page no: 36
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