All the following antimicrobial agents are used topically except –
Correct Answer: Griseofulvin
Description: Griseofulvin is used systemically for dermatophytosis. It is ineffective topically.
Polyene
Amphotericin B → Topically as well as systemically (oral, iv intrathecally.
Nystatin, Hamycin, Natamycin (Pimaricin) → Topically.
Hetrocyclic benzofuran
Griseofulvin → Systemically (oral)
Imidazoles
Clotrimazole, econazole, miconozole, oxiconazole → Topical.
Ketoconazole Systemically (oral) and topically.
Triazoles
Fluconazole, voriconazole → systemically (iv., oral) and itraconozole → systemically (orally).
Allylamine
Terbinafine → Systemically (oral) and topically.
Note
Amphotericin B, ketoconazole and terbinafine are used systemically as well as topically.
Category:
Dental
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