In apoptosis, the nucleus is destroyed by
Correct Answer: Endonuclease fragmentation
Description: In H&E-stained tissue sections, the nuclei of apoptotic cells show various stages of chromatin condensation and aggregation and, ultimately, karyorrhexis (Fig. 1-21); at the molecular level this is reflected in fragmentation of DNA into nucleosome-sized pieces. Ref Robbins 9/e p 18
Category:
Pathology
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