All of the following statements regarding streptokinase are true Except
Correct Answer: Its complex with plasminogen is inhibited by alpha 2 antiplasmin
Description: Streptokinase is a 47-kDa protein produced by beta-hemolytic streptococci. It forms a stable complex with plasminogen, which is not inhibited by antiplasmin. A large loading dose is given intravenously to overcome antibodies that may be formed from prior streptococcal infections. Being a foreign protein it may rarely cause anaphylaxis.
Category:
Pharmacology
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