Super antigen acts through?

Correct Answer: IL_1 & TNF
Description: Superantigens are ceain protein molecules such as staphylococcal enterotoxin, that stimulate large numbers of T cells irrespective of antigenic specificity. This leads to an excessive and dysregulated immune response with release of cytokines such as interleukin-1,2 and tumor necrosis factor and interferon gamma. Reference : Anathanarayan & paniker's 9th edition, pg no:90,203 <p>
Category: Microbiology
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