Aspirin irreversibly inhibits the following enzyme in the formation of eicosanoids:

Correct Answer: Cyclooxygenase
Description: Ans. B. CyclooxygenaseCyclooxygenase is required for the synthesis of prostaglandins by arachidonic acid. Aspirin, indomethacin, brufen, phenyl butazone and other NSAIDS inhibits COX (Cyclooxygenase). Aspirin inhibits COX of both PGHS-1 and PGHS-2 by acetylation
Category: Biochemistry
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