Azidothymidine (Zidovudine), commonest side effect is
Correct Answer: Macrocytic anaemia
Description: Ans. is 'd' i.e., Macrocytic anaemia "The most common adverse effect of zidovudine is myelosuppression, resulting in macrocytic anemia (1-4%) or neutropenia (2-8%)". So most common side effect of zidovudine is neutropenia (2-8%) followed by macrocytic anemia (1-4%). Other side effects are - nausea, anorexia, headache, insomnia, abdominal pain, myalgia, malaise, fatigue, myopathy, lactic acidosis, hepatomegaly with steatosis, convulsions and encephalopathy.
Category:
Pharmacology
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