Gene not involved in SCID

Correct Answer: BTK
Description: BTK gene is involved in Buon's disease or X linked agammaglobulinemia. Most cases of X linked Severe combined immunodeficiency (SCID) are due to mutations in IL2RG gene. Other mutations are defective enzyme production in Adenosine deaminase and mutations in ZAP -70 which causes defective T cell signalling which causes combined immunodeficiency and mutation occurs in JAK-3.
Category: Microbiology
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