Alkalinization of urine is required to treat toxicity of all except:
Correct Answer: Amphetamine
Description: Changes in urinary pH affect tubular reabsorption of drugs that are paially ionized - * Weak bases are ionize more and are less reabsorbed in acidic urine.* Weak acids ionize more and are less reabsorbed in alkaline urine. Urine is alkalinized in barbiturate, methotrexate and salicylate poisoning.
Category:
Pharmacology
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