Best indicator of Ovarian reserve :
Correct Answer: AMH
Description: None of the ovarian reserve tests currently in use are accurate predictors for pregnancy With current methods, basal FSH concentration is simplest and most widely used to test ovarian reserve. Levels greater than 10 IU/L (10-20 IU/L) have high specificity (80-100%) for predicting poor ovarian response to ovulation. Serum FSH levels vary significantly across the cycle hence FSH is best measured during early follicular phase ( cycle day 2-4). Basal serum estradiol concentration has little value as ovarian reserve test. AMH: Antimullerian hormone is produced from preantral and small antral follicles hence AMH levels are gonadotropin independent and exhibit little variation within and between menstrual cycles. AMH threshold levels (0.2-0.7ng/ml) has 40-97% sensitivity, 70-92% specificity, 22-88% PPV and 97-100% NPV for predicting poor response to stimulation (<3 follicles or < 2-4oocytes). Reference: chapter 27; Female infeility; Clinical gynecologic endocrinology - eighth edition
Category:
Gynaecology & Obstetrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now