Low serum haptoglobin in hemolysis is masked by ?
Correct Answer: Bile duct obstruction
Description: Ans. is 'c' i.e., Bile duct obstruction Haptoglobin o Haptoglobin is a transpo glycoprotein which binds free hemoglobin in plasma and carries it to the reticuloendothelial system. It is synthesized in the liver. o A decrease in haptoglobin levels (with normal liver function) occurs when there is excess of hemoglobin in the plasma due to intravascular hemolysis ---> free hemoglobin in plasma bound to haptoglobin and this complex is rapidly cleared by mononuclear phagocytic system. o In biliary obstruction the serum haptoglobin level is increased and this may mask the decrease in serum haptoglobin due to hemolysis.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now