Pro-inflammatory Cytokines include all of the following except –
Correct Answer: Interleukin-10
Description: Cytokines are involved in the immunological reaction, but some cytokines may also take part in inflammation.
o They may be: -
1. Proinflammatory cytokines
Involved in the amplification of inflammation and tissue destruction.
IL-1 & TNF-a are the two most important proinflammatory cytokines. IL-6 may also act as a proinflammatory cytokine.
Other proinflammatory cytokines are IL-2, IL-4, IL-5, IL-6, IL-8, IL-I1, IL-12, IL-15, IL-21, IL-23, IFN-gamma and granulocyte-macrophage colony-stimulating factor (GM-CSF). ( Source Fundamental immunology by William E. Paul).
2 Anti inflammatory cytokines
Reduce inflammation and produce healing,
Example are IL-4, IL-13, IL-1, IL-10
Category:
Pathology
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