7-methyl guanosine is added as a cap on mRNA. This methyl group is donated by:
Correct Answer: S-Adenosyl methionine (SAM)
Description: Capping is a post transcriptional modification. 7-methyl guanosine cap is added at the 5'end of mRNA by Guanylyl Transferase. Methyl group is donated by SAM (S-Adenosyl Methionine) by enzyme Guanine-7-Methyl Transferase, which occurs in cytoplasm (rest all post transcriptional modifications occur in nucleus). This cap facilitate initiation of translation and stabilize mRNA by preventing it from attack by 5' exonucleases. Cap is attached to 5' end of mRNA by an unusual 5' 5' triphosphate linkage.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now