Which among the following can prevent coagulation of blood:
Correct Answer: Sodium citrate
Description: Ans b: (Ref: Guyton 11th edition p466-467)Methods to present blood coagulation in vitro1 Siliconized containers - Present contact activation of platelets & Factor 82 Heparin - Especially is heart lung machine /artificial kidney3 Oxalate compunds - By precipitation of calcium oxalate compounds4 Citrate compounds(Sodium citrate, ammonium citrate, potassium citrate)- By deionization of blood calcium by forming an unionized calcium compound.But remember citrate anticoagulants are superior to oxalate anticoagulants because oxalate is toxic to body; but moderate quantities of citrate can be injected intravenously
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